= 5FU; n.
a drug that prevents cell growth (see antimetabolite) and is used in the treatment of solid tumours, such as cancers of the digestive system and breast (see also folinic acid). It is usually administered by intravenous infusion or injection; it is not well absorbed when taken by mouth, but oral fluoropyrimidines (e.g. capecitabine and tegafur/uracil) are converted to 5FU in the liver. Side-effects may include digestive and skin disorders, mouth ulcers, hair loss, nail changes, and blood disorders (see myelosuppression). Fluorouracil is also applied as a cream (Efudix) to treat certain skin conditions, including skin cancer.

The new mediacal dictionary. 2014.

Look at other dictionaries:

  • Fluorouracil — Systematic (IUPAC) name 5 fluoro 1H pyrimidine 2,4 d …   Wikipedia

  • Fluorouracil — Structure chimique du fluorouracil Général Nom IUPAC 5 fluoro 2,4(1H,3H) pyrimidinedio …   Wikipédia en Français

  • Fluorouracil — Strukturformel Allgemeines Freiname Fluorouracil Andere Na …   Deutsch Wikipedia

  • fluorouracil — A pyrimidine analog; an antineoplastic effective in the treatment of some carcinomas; the cells of certain neoplasms incorporate uracil into ribonucleic acid more readily than do normal tissue cells. SEE ALSO: floxuridine. * * * flu·o·ro·ura·cil …   Medical dictionary

  • fluorouracil — noun an antimetabolite used to treat certain cancers • Hypernyms: ↑antimetabolite * * * ˌ noun Etymology: fluor + uracil : a fluorine containing pyrimidine base C4H3FN2O2 used to treat some kinds of cancer; 5 fluorouracil * * * /floor euh yoor… …   Useful english dictionary

  • fluorouracil — noun Etymology: fluor + uracil Date: circa 1958 a fluorine containing pyrimidine base C4H3FN2O2 used as a neoplastic agent to treat some kinds of cancer …   New Collegiate Dictionary

  • fluorouracil — /floor euh yoor euh sil, flawr , flohr /, n. Pharm. a pyrimidine analog, C4H3FN2O2, used in the treatment of certain cancers. [FLUORO + URACIL] * * * …   Universalium

  • fluorouracil — noun A particular drug used in chemotherapy …   Wiktionary

  • Fluorouracil — Flu|o|ro|u|ra|cil: svw. ↑ Fluoruracil …   Universal-Lexikon

  • fluorouracil — flu·o·ro·uracil …   English syllables

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